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Statin Drugs
WASHINGTON (Reuters) - A diet rich in fiber and vegetables lowered cholesterol just as much as taking a statin drug, Canadian researchers reported on Monday.
They said people who cannot tolerate the statin drugs because of side-effects can turn to the diet, which they said their volunteers could easily follow.
David Jenkins of St. Michael's Hospital and the University of Toronto and colleagues created what they called a diet "portfolio" high in soy protein, almonds, and cereal fiber as well as plant sterols -- tree-based compounds used in cholesterol-lowering margarines, salad dressing and other products.
They tested their diet on 34 overweight men and women, comparing it with a low-fat diet and with a normal diet plus a generic statin drug, lovastatin.
Each volunteer followed each regimen for a month, with a break in between each treatment cycle.
Writing in the American Journal of Clinical Nutrition, Jenkins and colleagues said the low-fat diet lowered LDL -- the low-density lipoprotein or "bad" cholesterol -- by 8.5 percent after a month. Statins lowered LDL by 33 percent and the "portfolio" diet lowered LDL by nearly 30 percent.
The portfolio was rich in soy milk, soy burgers, almonds, oats, barley, psyllium seeds, okra and eggplant. The Almond Board of California helped fund the study, as did several food makers and the Canadian Natural Sciences and Engineering Research Council of Canada.
They also included a plant sterol margarine product. Several of these have been proven to lower cholesterol.
The researchers said nine volunteers, or a quarter of the group, got their lowest LDL levels from being on the portfolio diet.
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